Gunter Fischer Selected Research

Cyclophilin A

1/2020	Influences of cyclosporin A and non-immunosuppressive derivatives on cellular cyclophilins and viral nucleocapsid protein during human coronavirus 229E replication.
1/2020	Cyclophilin A/EMMPRIN Axis Is Involved in Pro-Fibrotic Processes Associated with Thoracic Aortic Aneurysm of Marfan Syndrome Patients.
1/2017	Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis.
10/2015	Targeting Extracellular Cyclophilins Ameliorates Disease Progression in Experimental Biliary Atresia.
3/2015	Extracellular cyclophilin A activates platelets via EMMPRIN (CD147) and PI3K/Akt signaling, which promotes platelet adhesion and thrombus formation in vitro and in vivo.
1/2015	The Novel Extracellular Cyclophilin A (CyPA) - Inhibitor MM284 Reduces Myocardial Inflammation and Remodeling in a Mouse Model of Troponin I -Induced Myocarditis.
5/2014	Human coronavirus NL63 replication is cyclophilin A-dependent and inhibited by non-immunosuppressive cyclosporine A-derivatives including Alisporivir.
11/2011	Oligopeptide cyclophilin inhibitors: a reassessment.

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Gunter Fischer Research Topics

Disease

9	Infections 01/2020 - 01/2003
5	Neoplasms (Cancer) 11/2019 - 11/2005
3	Inflammation (Inflammations) 10/2015 - 01/2015
3	Neuroblastoma 12/2007 - 05/2006
2	Virus Diseases (Viral Diseases) 01/2022 - 11/2011
2	Fibrosis (Cirrhosis) 10/2015 - 01/2015
2	Neurodegenerative Diseases (Neurodegenerative Disease) 04/2015 - 05/2006
2	Alzheimer Disease (Alzheimer's Disease) 08/2011 - 04/2006
1	Blister (Bulla) 01/2020
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2020
1	Hepatocellular Carcinoma (Hepatoma) 01/2020
1	Thoracic Aortic Aneurysm 01/2020
1	Abdominal Aortic Aneurysm 01/2020
1	Marfan Syndrome (Marfan's Syndrome) 01/2020
1	Reperfusion Injury 01/2019
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2017
1	Neuroinflammatory Diseases 01/2017
1	Disease Progression 10/2015
1	Weight Gain 10/2015
1	Biliary Atresia 10/2015
1	Atherosclerosis 06/2015
1	Thrombosis (Thrombus) 03/2015
1	Myocarditis (Carditis) 01/2015
1	Mitochondrial Diseases (Mitochondrial Disease) 09/2013
1	Pituitary Neoplasms (Pituitary Adenoma) 10/2012
1	Pneumonia (Pneumonitis) 12/2010
1	Autoimmune Diseases (Autoimmune Disease) 01/2010
1	Brain Ischemia (Cerebral Ischemia) 05/2006
1	Asthma (Bronchial Asthma) 04/2006
1	Anthrax 03/2005
1	Renal Tubular Acidosis (Distal Renal Tubular Acidosis) 01/2005
1	Legionnaires' Disease (Legionnaire's Disease) 08/2003

Drug/Important Bio-Agent (IBA)

8	Cyclophilin AIBA 01/2020 - 11/2011
6	Cyclophilins (Cyclophilin)IBA 01/2022 - 01/2005
6	Cyclosporine (Ciclosporin)FDA LinkGeneric 06/2015 - 01/2005
6	Peptidylprolyl Isomerase (Prolyl Isomerase)IBA 01/2015 - 01/2003
4	cis-trans-IsomerasesIBA 01/2017 - 05/2006
3	Tacrolimus Binding Proteins (FKBP)IBA 01/2019 - 05/2006
2	Basigin (Extracellular Matrix Metalloproteinase Inducer (EMMPRIN))IBA 01/2020 - 03/2015
2	Phosphotransferases (Kinase)IBA 11/2019 - 03/2015
2	Glucose (Dextrose)FDA LinkGeneric 11/2019 - 09/2013
2	Tacrolimus (Prograf)FDA LinkGeneric 01/2010 - 05/2006
2	Proteins (Proteins, Gene)FDA Link 05/2007 - 11/2005
2	Virulence Factors (Pathogenicity Factors)IBA 02/2007 - 08/2003
1	LuciferasesIBA 01/2020
1	alisporivirIBA 01/2020
1	(melle-4)cyclosporinIBA 01/2020
1	cyclophilin BIBA 01/2020
1	Pharmaceutical PreparationsIBA 11/2019
1	Adenosine Triphosphate (ATP)IBA 11/2019
1	Adenosine Monophosphate (AMP)IBA 11/2019
1	Equilibrative Nucleoside Transporter 1IBA 01/2019
1	Protein Isoforms (Isoforms)IBA 01/2019
1	Matrix Metalloproteinases (MMPs)IBA 10/2015
1	Tissue Inhibitor of MetalloproteinasesIBA 10/2015
1	ApolipoproteinsIBA 06/2015
1	tau Proteins (tau Protein)IBA 04/2015
1	Protein Kinases (Protein Kinase)IBA 04/2015
1	ferric chlorideIBA 03/2015
1	Troponin IIBA 01/2015
1	Dizocilpine Maleate (Dizocilpine)IBA 09/2013
1	Oxygen (Dioxygen)IBA 09/2013
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 09/2013
1	aryl hydrocarbon receptor-interacting proteinIBA 10/2012
1	IsoenzymesIBA 08/2011
1	CalcineurinIBA 01/2010
1	LigandsIBA 05/2006
1	Cycloheximide (Cicloheximide)IBA 05/2006
1	N- (N',N'- dimethylcarboxamidomethyl)cycloheximideIBA 05/2006
1	NIMA-Interacting Peptidylprolyl IsomeraseIBA 04/2006
1	Small Interfering RNA (siRNA)IBA 11/2005
1	AntigensIBA 03/2005
1	alpha-DefensinsIBA 03/2005
1	Immunosuppressive Agents (Immunosuppressants)IBA 01/2005
1	dirhodium tetraacetate (DRTA)IBA 01/2005
1	Legionella pneumophila Mip proteinIBA 01/2003

Therapy/Procedure

2	Therapeutics 01/2017 - 08/2010